Seun Elizabeth Kuyooro
P.M.B. 1015, Ota
Nigeria
Research Article
Hypolipidemic Effects of Irvingia gabonensis - Supplemented Diets in
Male Albino Rats
Author(s): Seun Elizabeth Kuyooro, Esther Omugha Abam and Elizabeth Bolaji AgbedeSeun Elizabeth Kuyooro, Esther Omugha Abam and Elizabeth Bolaji Agbede
Cardiovascular disease has become a disease of global concern. The present study investigated the effect of an Irvingia gabonensis - supplemented diet on cardiovascular disease risk. 24 male albino rats divided into 4 groups of 6 animals each were used. Diets containing varying amounts of Irvingia gabonensis seeds were prepared and fed to the rats for 4 weeks. Lipid profiles of the plasma total cholesterol, triacylglycerol, high-density liporotein (HDL) cholesterol and low density lipoprotein (LDL) cholesterol were determined. Generally, Irvingia gabonensis supplementation in diets resulted in reduced organ/body weight ratios. Total cholesterol, LDL-cholesterol levels and artherogenic indices were significantly reduced. The results of this study indicate that Irvingia gabonensis consumption has athero-protective potential as evidenced in the reduction in atherogenic indices in the rat.. View More»
DOI:
10.4172/2161-1009.1000316