Scalera F
Italy
Review Article
Recent Strategies in Osteochondral Substitutes Design: Towards the
Mimicking of a Multifaceted Anatomical Unit from the Nano to the Macro
Level
Author(s): Barbara Palazzo, Scalera F, Soloperto G, Scialla S and Gervaso FBarbara Palazzo, Scalera F, Soloperto G, Scialla S and Gervaso F
Nowadays regenerative medicine takes advantages not only of traditional implants, but also of engineered biocompatible parts, including degradable porous scaffolds integrated with cells or molecules. These approaches, positioned at the interdisciplinary area between biomedical materials science and medicine, will become more achievable when combined with biomimicry, which not only optimizes biomaterial interaction with biological tissues but also mimics biogenic materials in their structure and functionalities. Such methodologies are particularly attractive for bone and osteochondral related materials: in other words, cartilage and mineralized tissues are ideal example to learn-from in setting up biomaterial science researches. These tissues are highly integrated systems, having found a compromise between different properties and functions, above all thanks to their hierarchical struc.. View More»
DOI:
10.4172/2157-7439.1000458