Satya Prakash
Department of Biomedical Engineering, Department of Experimental Medicine, Faculty of Medicine, Biomedical Technology and Cell Therapy Research Laboratory,
3775 University Street, Montreal, Quebec, H3A2B4
Canada
Research Article
Ferulic Acid Produced by Lactobacillus fermentum NCIMB 5221 Reduces
Symptoms of Metabolic Syndrome in Drosophila melanogaster
Author(s): Susan Westfall, Nikita Lomis, Surya Pratap Singh and Satya Prakash
Susan Westfall, Nikita Lomis, Surya Pratap Singh and Satya Prakash
Abstract
The gut microbiota is an intricate community of thousands of bacterial species living in the gastrointestinal tract critical for vitamin synthesis, mineral absorption, digestion of otherwise indigestible fibers and the extraction of energy from food. Recently, the health of the gut microbiota’s community architecture has become linked to energy-regulatory diseases including metabolic syndrome: a collection of symptoms including hyperglycemia, hypercholesterolemia, high blood pressure, increased abdominal fat and triglyceride levels. However, the mechanism of communication between the gut microbiota and the host energy metabolism remains elusive. The current study shows that ferulic acid (FA) produced by the intrinsic ferulic acid esterase activity of the probiotic bacteria Lactobacillus fermentum NCIMB 5221 (Lf5221) can dose-dependent.. View More»
DOI:
10.4172/1948-5948.1000297