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Roy I
Roy I
India
Publications
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Research Article
Synthesis of Photoactive SPIONs Doped with Visible Light Activated Photosensitizer
Author(s): Kumar P, Agnihotri S and Roy IKumar P, Agnihotri S and Roy I
We have synthesized low cost and water dispersed citric acid coated iron-oxide nanoparticles at room temperature. TEM data were 10 shown the average diameter of these nanoparticles around 15 nm and XRD were then used to the crystalline nature of these particles. VSM experiment showed that these nanoparticles are superparamagnetic, with high magnetization (78 emu/g). In vitro studies have shown that these nanoparticles are nontoxic to human cells in culture. The citric acid coated superparamagnetic iron-oxide nanoparticles (CA-SPIONs) conjugated with a photosensitizer (PS-CA-SPIONs) for applications in photodynamic therapy (PDT). These PS-CA- SPIONs, stably-dispersed in aqueous medium, was characterized using optical studies. An Experiment involving light-activated 15 generation of reactive oxygen species (ROS) revealed that only the PS-CA-SPIONs, but not f.. View More»
DOI: 10.4172/2157-7439.1000392