Reena Tomar
India
Research Article
Phenotype Prevalence of Blood Group Systems (ABO, Rh, Kell) in Voluntary, Healthy Donors-Experience of a Tertiary Care Hospital in Delhi, North India
Author(s): Neeraj Garg, Deepak Kumar Singh, Reena Tomar and Bharat SinghNeeraj Garg, Deepak Kumar Singh, Reena Tomar and Bharat Singh
Objective: To study phenotypic prevalence of ABO, Rh and Kell blood group system. Material and Method: Voluntary blood donors were tested for red cell antigen of ABO, Rh (D, C, c, E, e) and Kell (K) blood group systems. Each sample was tested using LISS/Coombs ABO-Rh gel card and DiaClon Rh subgroups +K gel card. Calculations of antigen and phenotypes frequencies were expressed as percentages and allele frequencies were expressed under the standard assumption of Hardy-Weinberg equilibrium. Results: Study included a total of 2769 voluntary blood donors in which blood group distribution was (A-22.3%, B-39.2%, AB-8.9%, O-29.6%). Rh antigen was found positive in 93.8% and negative in 6.2% donors. Amongst Rh positive antigens, e was the most common (98.7%) followed by C (91.8%), c (55.2%) and E(21.1%). DCe/DCe (44.7%) was the most common phenotype. Distributions of Rh minor an.. View More»
DOI:
10.4172/2155-9864.1000297