PMC/PubMed Indexed Articles
Indexed In
- Open J Gate
- Genamics JournalSeek
- Academic Keys
- JournalTOCs
- ResearchBible
- China National Knowledge Infrastructure (CNKI)
- Scimago
- Ulrich's Periodicals Directory
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- MIAR
- Scientific Indexing Services (SIS)
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Rajveer Kaur
Rajveer Kaur
India
Publications
-
Research Article
Preparation and Evaluation of Hydrogel Nanoparticles as Drug Delivery System
Author(s): Rajveer Kaur, Vishal Kumar Gupta and Suresh Chandra PandeyRajveer Kaur, Vishal Kumar Gupta and Suresh Chandra Pandey
Hydrogel nanoparticles (NPs) can be used for colon drug delivery, utilizing Methotrexate (MTX) as a model drug. MTX loaded hydrogel NPs were prepared using Poly-acrylamide-grafted- gum ghatti (PAAm-g-Gg), which is pH sensitive. PAAm-g-Gg was synthesized by free radical polymerization. MTX loaded hydrogel NPs was prepared from PAAm-g-Gg by using nanoemulsification polymer crosslinking method. FT-IR and DSC studies of the prepared NPs indicated no chemical change of MTX in the hydrogel NPs. The prepared hydrogel NPs showed mean diameters in the range of 238 ± 0.57 nm to 1064 ± 0.99 nm. The encapsulation efficiency of the drug was found to be 39.11% to 48.84%. The suitability of the polyacrylamide grafted gum ghatti hydrogel NPs for the release of Methotrexate was studied by in vitro release at pH 1.2 and 7.4. It was observed that, there was no .. View More»
DOI: 10.4172/2157-7439.1000526