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Rajat Gothi
Rajat Gothi
India
Publications
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Review Article
Periodontal Ligament Stem Cells-The Regeneration Front
Author(s): Rajat Gothi,Naveen Sangwan,Ashutosh Kaushik*,Neha Sikka Rajat Gothi,Naveen Sangwan,Ashutosh Kaushik*,Neha Sikka
The principal cells of the healthy, functional periodontal ligament are the differentiated cells and their progenitors. The differentiated cells are concerned with the synthesis and resorption of alveolar bone and the fibrous connective tissue of the ligament and cementum. It has been shown that small proportion of periodontal ligament cells are in mitosis at any given time. The cells of the periodontal ligament are also highly active metabolically; those of the rat molar turn the collagen over 5 times faster than do the fibroblast in the lamina propria of gingiva and 15 times faster than the fibroblast of skin. Progenitor cells exhibited marked differences in cytodifferentiation, suggesting that the progenitor cells that divide after wounding do not belong to a population of cells exhibiting uniform cytological chara.. View More»
DOI: 10.4172/2161-1122.1000275