Periyathambi T
India
Review Article
Synthesis and Characterization of Schiff Base CoII, NiII and CuII Complexes Derived from 2-Hydroxy-1-naphthaldehyde and 2-Picolylamine
Author(s): Kadhiravansivasamy K*, Sivajiganesan S, Periyathambi T, Nandhakumar V, Chidhambram S and Manimekalai R
Kadhiravansivasamy K*, Sivajiganesan S, Periyathambi T, Nandhakumar V, Chidhambram S and Manimekalai R
New CoII, NiII and CuII complex has been synthesized and characterized by elemental analysis, UV-Vis, FT-IR and thermal analysis. binding of this CoII, NiII and CuII complex with calf thymus DNA was investigated by UV-Visible absorption, fluorescence spectroscopy techniques. The intrinsic binding constants Kb of complex with CT-DNA obtained from UV-Vis absorption studies were 4.43 × 105 M-1. Further, the in vitro cytotoxic effect of the complexes examined on cancerous cell line, such as human breast cancer cells (MCF-7).
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DOI:
10.4172/2329-6798.1000197