Advances in Pharmacoepidemiology and Drug Safety

Pawlowska M

Publications

• Review Article
  Antiviral Treatment in Patients with HCV-Associated Lymphoproliferative Disorders
  Author(s): Pawlowska M, Pilarczyk M and Halota WPawlowska M, Pilarczyk M and Halota W
  
  Clinical course of HCV infection may be connected with extra-hepatic manifestations associated with lymphoproliferative disorders as mixed cryoglobulinemia (MC) and non-Hodkin B cell lymphoma (B-NHL). The incidence of HCV infection in MC patients exceeds 80%, and among patients with B cell non-Hodgkin's lymphoma 10-17%, whereas this frequency is correlated with the prevalence of HCV in different geographic regions. 2015 European Association for the Study of the Liver (EASL) recommendations on Treatment of Hepatitis C prioritizes therapy of patients with extra-hepatic manifestations of HCV infection regardless of liver fibrosis. Antiviral treatment resulted in HCV RNA serum disappearance and tumor regression in the majority of patients with indolent B-NHL. It was revealed the high percentage of 5-year overall survival (OS), and 5-year progression-free survival (PFS) for t.. View More»
  DOI: 10.4172/2167-1052.1000190

  Abstract PDF