Journal of Nanomedicine & Nanotechnology

Pascale Schwinté

Publications

• Review Article
  Nano-Engineered Scaffold for Osteoarticular Regenerative Medicine
  Author(s): Pascale Schwinté, Laetitia Keller, Stéphanie Lemoine, Jacques-Eric Gottenberg, Nadia Benkirane-Jessel and Maximilien Vanleene Pascale Schwinté, Laetitia Keller, Stéphanie Lemoine, Jacques-Eric Gottenberg, Nadia Benkirane-Jessel and Maximilien Vanleene
  
  In the last decade, regenerative medicine has benefited from the exponential development of nanomaterial sciences, tissue engineering and cell-based therapies. More and more sophisticated designed structures and surface topologies are being developed to basically mimic the extracellular matrix of native tissues such as cartilage and bone. Here we give an overview of the progress made in osteochondral lesion repair, with nano-engineered scaffolds comprising building blocks such as nanoparticles, nanotubes, layer-by-layer nano-assemblies, molecular self-assembly, nanopatterned surfaces…. This nano-engineering technology is coupled with bio-functionalization, by the use of adhesion peptides, growth factors, or deoxyribonucleic acid, to drive cell adhesion, proliferation and behavior towards tissue regeneration. In osteochondral regeneration, the c.. View More»
  DOI: 10.4172/2157-7439.1000258

  Abstract PDF