Journal of Vascular Medicine & Surgery

Ozgur Karcioglu

Publications

• Review Article
  Untoward Effects in the Practice of Therapeutic Hypothermia: A Literature Update
  Author(s): Ozgur Karcioglu and Nazmiye KoyuncuOzgur Karcioglu and Nazmiye Koyuncu
  
  Out-of-hospital cardiac arrests (OHCA) is the plague of the modern day and therapeutic hypothermia (TH) is launched to be a remedy against this. TH is practised mainly in the treatment of adult cardiac arrest and neonatal hypoxic-ischemic encephalopathy. Despite the improved benefits of mild TH, there are commonly overlooked complications associated during management. TH may cause an increase in insulin resistance and a reduction in insulin levels which result in hyperglycemia. Studies showed a significantly increased incidence of meningitis, pneumonia and wound infections. Hypothermia was also reportedly associated with increased blood loss and transfusions. In addition, electrolyte abnormalities such as hypokalaemia, hypomagnesaemia, hypophosphatemia, hypo- and hyperglycaemia have been described during TH. The procedure has also been shown to incite mild metabolic acidosis. This art.. View More»
  DOI: 10.4172/2329-6925.1000356

  Abstract PDF