Journal of Nanomedicine & Nanotechnology

O’Malley BW

Publications

• Research Article
  A Novel Nano-approach for Targeted Inner Ear Imaging
  Author(s): Kayyali MN, Brake L, Ramsey AJ, Wright AC, O’Malley BW and Daqing Li DKayyali MN, Brake L, Ramsey AJ, Wright AC, O’Malley BW and Daqing Li D
  
  During the last decade, there have been major improvements in imaging modalities and the development of molecular imaging in general. However detailed inner ear imaging still provides very limited information to physicians. This is unsatisfactory as sensorineural hearing loss is the main cause of permanent hearing loss in adults and at least 134 genetic mutations that result in congenital hearing loss have been identified. We are still unable, in most cases where gross anatomical changes are not observed, to determine the exact cause of hearing loss at a cellular or molecular level in patients using non-invasive techniques. This limitation in inner ear diagnostic modalities is a major obstacle behind the delay in discovering treatments for many of the causes of sensorineural hearing loss. This paper initially investigated the use of targeted gold nanoparticles as contrast agents for i.. View More»
  DOI: 10.4172/2157-7439.1000456

  Abstract PDF