Clinical Microbiology: Open Access

Onaolapo JA

Publications

• Research Article
  Tetracycline Resistant Genes in E. coli Isolated from UTI and Diarrhea Patients in Zaria, Nigeria
  Author(s): Igwe JC, Musa A, Olayinka BO, Ehnimidu JO and Onaolapo JA Igwe JC, Musa A, Olayinka BO, Ehnimidu JO and Onaolapo JA
  
  Tetracycline (TC) is one of the widely used antibiotics for the treatment of infections with significant therapeutic effect due to its broad spectrum. But due to the emergence of high percentages of tetracycline resistance and the recent reoccurrence of multidrug resistance isolates in clinical settings, its use in hospitals have drastically reduced. This study evaluates the percentage of TC resistant in clinical isolates of E. coli from UTI and diarrhea patients in Zaria, Nigeria. Out of the 86 E. coli isolates collected from 4 hospitals for the period of 6 months (April-September, 2014), 68.6% (59) were observed to be resistant to TC using both disc diffusion and MIC (range of ≥ 4 μg/ml) methods. The antibiotic susceptibility profile of the isolates showed that the isolates had varied antibiotic resistant profile to the 14 antibiotics tested. Significant perce.. View More»
  DOI: 10.4172/2327-5073.1000225

  Abstract PDF