Clinical Microbiology: Open Access

Onaolapo JA

Publications

• Research Article
  Impact of Outer Membrane Protein OmpC and OmpF on Antibiotics Resistance of E. coli Isolated from UTI and Diarrhoeic Patients in Zaria, Nigeria
  Author(s): Igwe JC, Olayinka BO, Ehnimidu JO and Onaolapo JA Igwe JC, Olayinka BO, Ehnimidu JO and Onaolapo JA
  
  Multidrug resistant (MDR) E. coli associated infections remains one of the most important bacterial infections that have contributed significantly to increased morbidity and mortality in clinical settings. One of the known resistant mechanisms of MDR bacteria is reduced cell wall permeability, which is controlled by outer membrane protein OmpF and OmpC. This study evaluates the difference in molecular weight of outer membrane protein of MDR E. coli isolated from UTI and diarrhoeic patients in Zaria, Nigeria and antibiotic susceptible ATCC29522 strain using standard microbiological and molecular techniques. Eighty seven (87) confirmed E. coli isolates from UTI and diarrhoeic patients in selected hospitals in Zaria, Nigeria were evaluated for MDR using 15 antibiotics commonly prescribed for E. coli associated infections. The results showed that the 21 suspected multidrug isolates were 1.. View More»
  DOI: 10.4172/2327-5073.1000267

  Abstract PDF