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Okoko Tebekeme
Okoko Tebekeme
Nigeria
Publications
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Research Article
Lipidemic Properties of Sorghum vulgare Leaf Sheath on Oxidative Markers and Heart Function Enzymes of Dyslipidemic Wistar-Albino Rats
Author(s): Akuru Udiomine B and OkokoTebekemeAkuru Udiomine B and OkokoTebekeme
Dyslipidemia is an abnormal amount of lipids such as triglycerides, cholesterol and/or fat phospholipids in the blood. The aim of this study was to investigate the lipidemic properties of Sorghum vulgare leaf sheath on oxidative markers and heart function enzymes on high-fat-diet induced dyslipidemic wistar-albino rats. Thirty-six (36) wistar-albino rats weighing 110-130 g were used for the study. The animals were distributed randomly into six groups of six animals each. Group 1 (control), group II to group VI were fed with high fat diet; group II (untreated), groups III to V received 400 mg/kg, 800 mg/kg and 1200 mg/kg aqueous extract of Sorghum vulgare leaf sheath respectively while group VI was treated with atorvastatin (0.2 mg/kg) which is a standard drug. The results of the study showed that aqueous extract of Sorghum vulgare leaf sheath (especially at .. View More»
DOI: 10.4172/2161-1009.1000343