Journal of Nanomedicine & Nanotechnology

Okafor Ijeoma

Publications

• Research Article
  Rifampicin-loaded Silver-starch Nanocomposite for the Treatment of Multi-resistant Tuberculosis
  Author(s): Isimi Christianah, Asha Rodrigues, Okafor Ijeoma, Okoh Judith, Aboh Mercy and Emeje Ma rtins Ochubiojo Isimi Christianah, Asha Rodrigues, Okafor Ijeoma, Okoh Judith, Aboh Mercy and Emeje Ma rtins Ochubiojo
  
  Extraction, purification and synthesis of acetylated cassava starch was undertaken. The degree of modification for the acetylated (modified) starch was calculated to be 0.03. Physicochemical indices interrogated were all significantly (P<0.05) affected by the acetylation. Microstructural studies revealed starches that were predominantly polygonal in shape. The FTIR results confirmed introduction of an acetyl group with a new band at 1728 cm-1. The results further show that, the modification did not degrade the granule morphology, but x-ray pattern showed increased crystallinity in the acetylated derivative. Thermogravimetric analysis and differential scanning calorimetry revealed 2 phase decomposition of both starches and improved gelation capacity with new peaks respectively. Rifampicin (RIF) loaded starch-stabilized silver nanoparticles yielded good mean particle size (248 nm), p.. View More»
  DOI: 10.4172/2157-7439.1000374

  Abstract PDF