Nwankwo OVU
Nigeria
Research Article
Comparative Effects of Ethanolic Extract of Gongronema latifolium and Piper guineense on Blood Electrolytes in Ethanol Exposed Wistar Rats
Author(s): Ali Fredrick U, Ominyi MC, Nwankwo OVU, Ibiam UA and Ogbanshi ME
Ali Fredrick U, Ominyi MC, Nwankwo OVU, Ibiam UA and Ogbanshi ME
Aim: The effects of ethanolic extract of Gonngronema latifolium and Piper guineense on serum electrolytes, function indices and liver marker enzymes on wistar rats exposed with ethanol were investigated.
Methology: Forty male albino rats (weighing 150-220 g) were used. The animals were divided into four groups A, B, C, and D with C and D subdivided into four subgroups; C1, C2, C3 and C4; D1, D2, D3 and D4 for G. latifolium and Piper guineense respectively, each contained four rats. Group B, and sub groups C and D rats were exposed with 70% ethanol for 7 days to induce liver damage and later treated group C and D with ethanol extracts for 21 days. The following quantities were administered orally to the albino rat per kg body weight: 200, 400,600, and 800 mg; while 0.9% normal saline was served to both the control group. The .. View More»
DOI:
10.4172/2161-1009.1000179