Journal of Nanomedicine & Nanotechnology

Nikhil Ranjan Jana

Publications

• Research Article
  Therapeutic use of Fisetin and Fisetin Loaded on Mesoporous Carbon Nanoparticle (MCN) in Thioglycollate-induced Peritonitis
  Author(s): Shinjini Mitra, Silpak Biswas, Aryabaran Sinha, Nikhil Ranjan Jana and Ena Ray BanerjeeShinjini Mitra, Silpak Biswas, Aryabaran Sinha, Nikhil Ranjan Jana and Ena Ray Banerjee
  
  Background: The pathophysiology of aseptic peritonitis involves inflammation of the serosal membrane that lines the abdominal cavity and the organs contained therein. The etiology of peritonitis is complicated and is involved in various processes, of which, the most important one is the inflammatory reaction. During the pathological process of peritonitis, NF-κB plays an activating role in the inflammatory reaction, which might be a potential therapeutic target in the therapy of certain inflammatory diseases. We studied the anti-inflammatory and pro-regenerative actions of Fisetin, a flavonol found in many plants, in a mouse model of thioglycollate-induced peritonitis, as well as the actions of fisetin administered with a nanoparticle such as mesoporous carbon nanoparticle (MCN). BALB/c mice were used in this study. Results: We found cell recruitment.. View More»
  DOI: 10.4172/2157-7439.1000332

  Abstract PDF