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Nigusse ZT
Nigusse ZT
Ethiopia
Publications
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Research Article
Screening of Aloe otallensis Exudate and Its Effect on Leishmania aethiopica
Author(s): Nigusse ZT, Wondifraw WA and Abate SM Nigusse ZT, Wondifraw WA and Abate SM
Background and objectives: The different Aloaceae plant extracts have been tested and found to contain components with anti leishmanial activity. Our study was conducted to assure anti leishmanial activity of the methanol extract of Aloe otallensis on the promastigot stage of Leishmania aethiopica as compared to currently used drugs and also tried to screen its phytochemical constitutes. Methods: Aloe otallensis leaf exudate was extracted by using methanol solvent and phytochemical screening was done using the method mentioned by Trease and Evans as well as the extract was evaluated for in vitro anti leishmanial activity against Leishmania aethiopica which was taken from the Black Lion Specialized Hospital parasitology unit. The result was compared with currently used drug like; Sodium stibogluconate, milfostin and paramomycin. .. View More»
DOI: 10.4172/2153-2435.1000515