Neveen Said

Neveen Said

P.O. Box 800383, Charlottesville, VA 22908- 0422
Tanzania

Publications
  • Review Article
    Secreted Protein Acidic and Rich in Cysteine (SPARC) in Cancer
    Author(s): Neveen Said and Dan TheodorescuNeveen Said and Dan Theodorescu

    The local tissue microenvironment “niche” is composed of cellular and non-cellular components and plays an important role in regulating cell behaviour, during embryogenesis, and in physiologic and pathologic contexts including cancer. The cellular component is formed of specialized cell types endowed for the biological functions of the organ and tissues. The non-cellular component of the niche comprises the extracellular matrix (ECM) which functions not only as a scaffold for the cellular component maintaining tissue morphology, but dynamically influences fundamental aspects of cell behaviour. Matricellular proteins are a group of extracellular matrix (ECM) molecules that are not components of the structural scaffold of the ECM but serve as cell regulators and modulators of cellular behaviour and signaling. Secreted Protein Acidic and Rich in Cysteine (SPARC) is one of the.. View More»
    DOI: 10.4172/2157-2518.1000151

    Abstract PDF