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Nahla Sameh
Nahla Sameh
Benisuef
Egypt
Publications
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Review Article
Prospective Role of Simvastatin on Wound Healing: Review of the Literature
Author(s): Nahla Sameh, Usama F Aly, Heba A Abou-Taleb and Ahmed AH Abdellatif Nahla Sameh, Usama F Aly, Heba A Abou-Taleb and Ahmed AH Abdellatif
Background: Wound healing is a normal biological complex and dynamic process of substituting injured and misplaced cellular structures and tissue layers. This complicated development is achieved through four different phases: haemostasis, inflammation, proliferation, and finally remodelling. These four phases must occur in the proper sequence and time frame to achieve successful wound healing. Over years topical antibiotics were applied on wounds but it causes side effects and resistance; that’s why it was a necessity to find a new topical wound healing drugs rather than antibiotics. Methods: Literature was searched in NCBI (The National Center for Biotechnology Information Advances Science and Health), Wiley online library, ScienceDirect database using the keywords Simvastatin, wound healing, Topical formulation. Articles that seemed sui.. View More»
DOI: 10.4172/0975-0851.1000375