N Chandrasekaran
India
Research Article
Drug Delivery System for Controlled Cancer Therapy Using Physico-Chemically Stabilized Bioconjugated Gold Nanoparticles Synthesized from Marine Macroalgae, Padina Gymnospora
Author(s): Manoj Singh, Manish Kumar, S Manikandan, N Chandrasekaran, Amitava Mukherjee and AK KumaraguruManoj Singh, Manish Kumar, S Manikandan, N Chandrasekaran, Amitava Mukherjee and AK Kumaraguru
Gold nanoparticles (AuNPs) have always been considered as superior tools for biosystem applications owing to their characteristic optical properties in form of surface plasmon resonance and amperometric properties with very low or no immediate toxicity. Biosystem application based tools have been designed based on many studies with gold nanoparticles but the reduction of bulk material to nanosized particle in conjugation with biomolecules in a physicochemical environment is an area requiring deeper investigation. In the present study complementary high resolution imaging techniques on different length scale are applied to elucidate morphology of gold nanoparticles. The biomolecules involved in conjugation and reduction were further characterized. The impact of macroalgae broth concentration on formation of AuNPs (8-21 nm) were further studied to determine the functional and molecular .. View More»
DOI:
10.4172/2157-7439.S5-009