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Mokembo Justin Nyakang’o
Mokembo Justin Nyakang’o
Uganda
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Research Article
Design of a Recombinant Hepatitis B Vaccine Based on Stably Binding HLA-I Peptides
Author(s): Miruka Conrad Ondieki, Matunda Conradus Nyaribari, Nnamdi John Ejekwumadu and Mokembo Justin Nyakang’o Miruka Conrad Ondieki, Matunda Conradus Nyaribari, Nnamdi John Ejekwumadu and Mokembo Justin Nyakang’o
The hepatitis B virus continues to infect many millions of people worldwide. There is a need to develop new vaccines against the virus. Using immunoinformatics approaches, we have predicted epitopes within the hepatitis B virus surface antigen that can be used to develop a new vaccine. The predicted epitopes were then used to construct a synthetic vaccine. The interaction between the synthetic vaccine construct and major histocompatibility complex was also predicted using bioinformatics tools. .. View More»
DOI: 10.4172/2167-7956.1000120