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Mohammad Reza Khodaie Ardakani
Mohammad Reza Khodaie Ardakani
West Indies
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Research Article
Identifying Some Risk Factors of Time to Recurrent Relapses in Bipolar I Disorder Patients using Frailty Model of Survival Analysis
Author(s): Seyede Solmaz Taheri, Mohammad Reza Khodaie Ardakani, Masoud Karimlou and Mehdi RahgozarSeyede Solmaz Taheri, Mohammad Reza Khodaie Ardakani, Masoud Karimlou and Mehdi Rahgozar
Objective: Bipolar I disorder patients often experience relapse once and even more with no limit on number of relapses. The time to relapses of these patients are rarely studied particularly considering heterogeneity across individuals. The aim of this study was to identify some risk factors of time to recurrent relapses in bipolar I disorder patients with a recurrent event model in survival analysis. Methods: In a retrospective longitudinal study, data of medical records of 526 bipolar I disorder patients who had referred to Razi Psychiatric hospital in Tehran from 1993 to 2011 with at least one relapse, with-out relapse in other hospitals or home in this duration, were investigated and time to recurrent relapses were collected in months. Semiparametric penalized frailty model which consider whit-in subject correla.. View More»
DOI: 10.4172/2378-5756.1000376