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Mohamed R El-Aassara
Mohamed R El-Aassara
Egypt
Publications
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Research Article
Novel Trend in Colon Cancer Therapy Using Silver Nanoparticles Synthesized by Honey Bee
Author(s): Nehal M El-Deeb, Ibrahim M El-Sherbiny, Mohamed R El-Aassara and Elsayed E Hafez Nehal M El-Deeb, Ibrahim M El-Sherbiny, Mohamed R El-Aassara and Elsayed E Hafez
Recently, the biosynthesis of nanoparticles has been well explored which draws attention to its possible biomedical applications especially in cancer therapy. In the current study, the novelty in the biosynthesis of silver nanoparticles (AgNPs) using honey bee extract has been explained. This study was also aiming at investigating the anti-colon cancer activities of the biogenic AgNPs along with its capping biomolecules in vitro. The obtained biogenic AgNPs were well characterized by X-ray diffraction (XRD), energy dispersive X-ray (EDX), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). It was found that the formed AgNPs have spherical shape with size range from 12 to 18 nm embedded in honey bee biomolecules. The cytotoxicity results of AgNPs on peripheral blood mononuclear cells (PBMC) indicated that the obtain.. View More»
DOI: 10.4172/2157-7439.1000265