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Milena Pereira Pondé
Milena Pereira Pondé
Brazil
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Review Article
Antidepressants in Pregnancy and Autism Spectrum Disorder: A Systematic Review
Author(s): Antônio Carlos C Freire, Camila CM de Oliveira and Milena Pereira PondéAntônio Carlos C Freire, Camila CM de Oliveira and Milena Pereira Pondé
Purpose: To determine the risk of autism spectrum disorder (ASD) in children following antidepressant use in pregnancy. Methods: A systematic review using the CAPES platform for the January 2005 to May 2015 period. The descriptors used were (antidepressant) and (pregnancy) and (autism). Articles were selected based on preestablished inclusion/exclusion criteria, with quality evaluated using the STROBE checklist. Results: Six articles were evaluated, with five favoring some form of association between antidepressant use in pregnancy and ASD in the child. In one paper, this association was found only with boys, while another identified the risk in children exposed to maternal depressive symptoms with no use of selective serotonin reuptake inhibitors. Conclusion: Results show that in addition to the multiple factors linked to antidepressant use in pregnancy and child development, factors.. View More»
DOI: 10.4172/2378-5756.1000392