Journal of Stem Cell Research & Therapy

Milan Patel

Publications

• Review Article
  Human Umbilical Cord Blood for Transplantation Therapy in Myocardial Infarction
  Author(s): Sandra A Acosta, Nick Franzese, Meaghan Staples, Nathan L Weinbren, Monica Babilonia, Jason Patel, Neil Merchant, Alejandra JacotteSimancas, Adam Slakter, Mathew Caputo, Milan Patel, Giorgio Franyuti, Max H Franzblau, Lyanne Suarez, Chiara Gonzales-Portillo, Theo Diamandis, Kazutaka Shinozuka, Naoki Tajiri, Paul R. Sanberg, Yuji Kaneko, Leslie W Miller Sandra A Acosta, Nick Franzese, Meaghan Staples, Nathan L Weinbren, Monica Babilonia, Jason Patel, Neil Merchant, Alejandra JacotteSimancas, Adam Slakter, Mathew Caputo, Milan Patel, Giorgio Franyuti, Max H Franzblau, Lyanne Suarez, Chiara Gonzales-Portillo, Theo Diamandis, Kazutaka Shinozuka, Naoki Tajiri, Paul R. Sanberg, Yuji Kaneko, Leslie W Miller
  
  Cell-based therapy is a promising therapy for myocardial infarction. Endogenous repair of the heart muscle after myocardial infarction is a challenge because adult cardiomyocytes have a limited capacity to proliferate and replace damaged cells. Pre-clinical and clinical evidence has shown that cell based therapy may promote revascularization and replacement of damaged myocytes after myocardial infarction. Adult stem cells can be harvested from different sources including bone marrow, skeletal myoblast, and human umbilical cord blood cells. The use of these cells for the repair of myocardial infarction presents various advantages over other sources of stem cells. Among these are easy harvesting, unlimited differentiation capability, and robust angiogenic potential. In this review, we discuss the milestone findings and the most recent evidence demonstrating the therapeutic efficacy and .. View More»
  DOI: 10.4172/2157-7633.S4-005

  Abstract PDF