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Mikio Arita
Mikio Arita
Japan
Publications
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Case Report
The Efficacy of L-Carnitine for Fanconis Syndrome caused by Long-Term Administration of Adefovir Dipivoxil(Adv) in a Patient with Chronic Hepatitis B: A Case Report
Author(s): Hiroto Tanaka, Hideyuki Sasaki and Mikio Arita Hiroto Tanaka, Hideyuki Sasaki and Mikio Arita
A 51-year-old female with chronic hepatitis B treated by Lamivudine (LAM) and Adefovir Dipivoxil (ADV) because of breakthrough hepatitis developed hypophosphatemia. She was diagnosed with Fanconi’s syndrome caused by the long-term administration of ADV. Since her symptoms did not improve after decreasing the ADV dosage and administering vitamin D, she was given L-carnitine. This led to a gradual improvement of her symptoms and the hypophosphatemia. These results indicate that a decrease in the ADV dose combined with supplementation with L-carnitine led to an improvement of Fanconi’s syndrome acquired by a patient with chronic hepatitis B while taking ADV. .. View More»
DOI: 10.4172/2167-0889.1000189