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Miji Lee
Miji Lee
Republic of Korea
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Research Article
Effectiveness of Antipsychotics on Delirium in Elderly Patients
Author(s): Miji Lee, Taeseung Kim, Sohyun Ahn and Jeong Lan KimMiji Lee, Taeseung Kim, Sohyun Ahn and Jeong Lan Kim
Study background: Delirium is common in older adults, but the pharmacological treatment of delirium in the elderly has not been established. This study aimed to compare the efficacy of three atypical antipsychotics (amisulpride, quetiapine, and risperidone) for the treatment of delirium in patients aged >65 years. Methods: Psychiatrists examined subjects aged >65 years referred to the consultation–liaison psychiatry service for at baseline, day 3, and day 7. Totally, 129 subjects were enrolled and assigned to receive either amisulpride (n=44), quetiapine (n=44), risperidone (n=21), or not to receive any antipsychotic medications (n=20). We examined the efficacy of each medication using the Korean version of the Delirium Rating Scale-Revised-98, which investigates the severity of delirium episodes. We then evaluated the cognitive function of subjects using the Mini-Mental S.. View More»
DOI: 10.4172/2378-5756.1000411