Michelle M Mielke
Tanzania
Research Article
Leptin, Adiponectin and Cognition in Middle-aged HIV-infected and Uninfected Women. The Brooklyn Womens Interagency HIV Study
Author(s): Deborah R Gustafson, Michelle M Mielke, Sheila A Keating, Susan Holman, Howard Minkoff and Howard A Crystal
Deborah R Gustafson, Michelle M Mielke, Sheila A Keating, Susan Holman, Howard Minkoff and Howard A Crystal
Context: Case-control study of women with and without HIV infection. Objective: To explore the association of cognition and the adipokines, leptin and adiponectin (total; high molecular weight, HMW), in women with (HIV+) and without HIV (HIV-) infection. Design: Cross-sectional analyses of adipokines and cognition using linear regression models of log-transformed adipokines, and Trails A, Trails B, Stroop interference time, Stroop word recall, Stroop color naming and reading, and Symbol Digit Modalities Test (SDMT) with consideration for age, HIV infection status, education, CD4 count, diabetes, body mass index (BMI), waist circumference (WC) and race/ethnicity. Setting: Brooklyn, NY. Participants: 354 participants (247 HIV+, 107 HIV-), in the Brooklyn Women’s Interagency HIV Study (WIHS), average age 38.9 years, with measured levels of leptin and adiponectin (total and high mol.. View More»
DOI:
10.4172/2167-7182.1000240