Journal of Nanomedicine & Nanotechnology

Michel Daudon

Publications

• Research Article
  Infrared Microspectroscopy using Synchrotron Radiation (Sr Μftir) and Infrared Microspectroscopy as New Tools for Rapid Detection of Ectopic Calcifications Associated with Peritoneal Dialysis
  Author(s): Agnieszka A Pozdzik, Pieter Demetter, Monika Tooulou, Anwar Hamade, Joelle Nortier, Dominique Bazin and Michel DaudonAgnieszka A Pozdzik, Pieter Demetter, Monika Tooulou, Anwar Hamade, Joelle Nortier, Dominique Bazin and Michel Daudon
  
  The cardiovascular calcifications (CVC) represent a central complication of chronic kidney disease (CKD) responsible of high cardiovascular mortality particularly in patients on peritoneal dialysis. Unfortunately, electron beam and multislice computed tomography, planar X-ray, ultrasonography or cardiac echocardiography methods are not accurate to detect calcium phosphate microcrystals since of its small size. We investigated the ectopic calcifications by Von Kossa staining and infrared microspectroscopy using synchrotron radiation (SR μFTIR) and infrared microspectroscopy in formalinfixed peritoneal tissues from 3 cases. Von Kossa staining allowed us to detect vascular calcifications only in one of 3 studied peritoneal biopsies. Vascular calcifications contained mainly carbapatite accordingly to the presence of the IR absorption bands positioned at 103.. View More»
  DOI: 10.4172/2157-7439.1000342

  Abstract PDF