Journal of Bioequivalence & Bioavailability

Maxwell Kim Kit Lee

Publications

• Research Article
  Drug Development in Cell Culture: Crosstalk from the Industrial Prospects
  Author(s): Maxwell Kim Kit Lee and DilqMaxwell Kim Kit Lee and Dilq
  
  The molecular medicine and technology undoubtedly can accelerate the new pharmacophores industrial development. Even though there are many highly-efficient screening methods can be applied in the research, but we still have problems on how to explain these data qualities in the early experimental designs. The researchers recently are just focusing on the animals studies for the drug registration but this method is time-consuming, costly and harmful to animals. Therefore, we need not just focus on the biological parameters and combine them together with the absorption, distribution, metabolism, excretion and toxicity (ADMET) property, permeability and solubility for the optimization study, the cell culture system also play crucial role in the drug candidate development. In conversely to the animals study, the in-vitro cell culture methods are characterized by the low compound requireme.. View More»
  DOI: 10.4172/jbb.10000188

  Abstract PDF