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Maxwell Kim Kit Lee
Maxwell Kim Kit Lee
Indiana
Publications
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Review Article
Crosstalk the Microdialysis in Scientific Research: from Principle to its Applications
Author(s): Maxwell Kim Kit Lee and Liuqing DiMaxwell Kim Kit Lee and Liuqing Di
The microdialysis technique is an invasive, expensive and a new real-time continuous in vivo sampling technique. The microdialysis technique with high sensitivity, good selectivity of modern analytical techniques combined with truly online real-time in vivo determination of the endogenous substances and drugs, which can effectively shorten the sampling time and increase the sample stability, can save time and cost savings and improve time resolution to accurately observe the rapid changes that are a major breakthrough in vivo drug analysis. When considering the need for on-line coupled with analysis of microdialysis, the probe recovery, perfusion rate, relative molecular weight analytes, such as the impact on the recovery of the probe, as well as analysis requires sample volume, analytes concentration range, the methods of the sample and related factors limit of quantification, analys.. View More»
DOI: 10.4172/2153-2435.1000276