Journal of Allergy & Therapy

Martyna Wesserling

Publications

• Research Article
  Lelp-1, Its Role in Atopic Dermatitis and Asthma: Poland and Portugal
  Author(s): Margarida Cortez, Andreia Matos, Martyna Wesserling, Tadeusz Pawelczyk, Magdalena Trzeciak and Manuel Bicho Margarida Cortez, Andreia Matos, Martyna Wesserling, Tadeusz Pawelczyk, Magdalena Trzeciak and Manuel Bicho
  
  Background: Atopic dermatitis(AD) that begins in childhood and is the first step of the so-called 'atopic march'. The chromosome 1q21 region has been associated with AD and psoriasis, with a peak in Epidermal Differentiation Complex (EDC) in a region of 2.05 Mb. The aim of this work was to study LELP-1 (late cornified envelope-like proline-rich 1) polymorphism [rs7534334] located within the EDC, in AD and asthma in two European populations: Portugal and Poland. Methods: We studied 110 individuals in the control group and 129 asthmatics in the Portuguese cohort; 100 controls and 45 patients with AD and asthma in the Poland cohort. Written informed consent was obtained from all participating individuals. LELP-1 genotypes were determined by the PCR-RFLP technique. All statistical analyses were carried out using SPSS 21.0 software. Results: The results were considered statisticall.. View More»
  DOI: 10.4172/2155-6121.1000229

  Abstract PDF