Journal of Allergy & Therapy

Martin R Lindley

Publications

• Research Article
  The Effect of Combining Fish Oil and Vitamin C on Airway Inflammation and Hyperpnea-Induced Bronchoconstriction in Asthma
  Author(s): Timothy D Mickleborough and Martin R Lindley Timothy D Mickleborough and Martin R Lindley
  
  Purpose: To compare the effects of two mono-therapies (fish oil and vitamin C) alone and in combination, on airway inflammation and the bronchoconstrictor response to eucapnic voluntary hyperpnea (EVH) in asthmatics. Methods: Sixteen asthmatic subjects with hyperpnea-induced bronchoconstriction (HIB) entered the study on their usual diet (pre-treatment, n=16) and then randomly assigned to receive either active vitamin C tablets (1.5 g) and placebo fish oil capsules (n=8) or active fish oil capsules (3.2 g EPA/2.0 g DHA) and placebo vitamin C tablets (n=8) taken for 3 weeks. Thereafter, all subjects (combination treatment; n=16) underwent a further 3-week treatment period consisting of active vitamin C tablets and active fish oil capsules taken daily (NT01057615). Results: HIB was significantly inhibited (p<0.017) by fish oil, vitamin C and combination treatment .. View More»
  DOI: 10.4172/2155-6121.1000184

  Abstract PDF