Maria Canillas
Spain
Research Article
Novel Nanostructured Zn-substituted Monetite Based Biomaterial for Bone Regeneration
Author(s): Sussette Padilla, Arcadio García de Castro, Ana Garzón-Gutiérrez, Lorena Benito, Silvia Enciso, Maria Canillas, Raú and G Carrodeguas
Sussette Padilla, Arcadio García de Castro, Ana Garzón-Gutiérrez, Lorena Benito, Silvia Enciso, Maria Canillas, Raú and G Carrodeguas
A bone regeneration biomaterial must be biocompatible, osteoconductive and osteoinductive, and be gradually replaced by newly formed bone in the shorter time possible. Nanostructured materials, emulating bone composition and morphology, have shown great potential in bone repair because of their higher reactivity, faster reabsorption and improved biological behavior over microstructured materials.
This work was aimed at developing a new biomaterial that meets the requirements for effective bone regeneration. Combination of elements with different solubility such as monetite, hydroxyapatite, amorphous calcium phosphate and silica gel, provided with the means to modulate the rate of material reabsorption of this novel biomaterial were Zn was found to be present as a partial substitution of Ca in the monetite lattice. The biomat.. View More»
DOI:
10.4172/2157-7439.1000325