Biology and Medicine

Marco Manfredi

Publications

• Research Article
  Helicobacter Pylori Infection: We Should Always Verify the Intrafamilial Transmission
  Author(s): Marco Manfredi, Silvia Iuliano, Pierpacifico Gismondi, Barbara Bizzarri, Federica Gaiani, Alessia Ghiselli and Gian Luigi de’AngelisMarco Manfredi, Silvia Iuliano, Pierpacifico Gismondi, Barbara Bizzarri, Federica Gaiani, Alessia Ghiselli and Gian Luigi de’Angelis
  
  Background and Aims: Helicobacter pylori infection is one of the most common gastrointestinal infections in humans; it affects about 30% of people in developed countries and about 80% in developing ones. The majority of patients acquire the infection during childhood and the intrafamilial transmission is considered one of the most important routes of infection. The aim of this study was to assess the intrafamilial transmission rate among family members of index subjects. Methods: We have suggested all patients H. pylori-positive (99 patients, symptomatic index subjects) diagnosed during 18 months (Sep 2011-Dec 2012) to screen their family members by stool antigen test (SAT) and, when positive, to perform upper gastrointestinal endoscopy. Results: Through SAT we identified 126 patients belonging to 41 households of 99 initial index subjects, therefore 41 index subjects (41.4%) had at l.. View More»
  DOI: 10.4172/0974-8369.1000366

  Abstract PDF