Mahasen Wadi
College of Applied Medical Sciences, Department of Clinical Laboratory Sciences Riyadh
Saudi Arabia
Case Report
Treatment of Cutaneous Leishmaniasis by Topical Application of Honey
Author(s): Mahasen Wadi, Al Fadhil Al Obeid and Sami KhalidMahasen Wadi, Al Fadhil Al Obeid and Sami Khalid
Objective: The objective of this study is to evaluate the effect of topical application of honey on induced cutaneous leishmaniasis ulcer in 25 hamsters (Mesocircetus auratus) compared with control group of another 25 hamsters treated by pentostam injection.
Methods: A group of 50 adult male and female hamsters, were inoculated with 1×105 cells/mL of Leishmania major. Culture medium was examined microscopically for promastigotes. Samples of 0.1 ml positive culture were inoculated to the hamster –tail base intradermally. The animasl were checked for lesion. Which were taken impression smear.. Smears were fixed and stained with Giemsa’s. Honey was applied topically to infected lesions of one group of hamsters. The control group were injected with 0.1 mL pentostam intramuscular every other day. Lesions were measured daily by m.. View More»
DOI:
10.4172/2155-9597.1000110