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Magdalena Nauerth
Magdalena Nauerth
Germany
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Short Article
Relevance of the T cell Receptor-Ligand Avidity for Immunity to Infection
Author(s): Magdalena Nauerth, Kristof Wing, Heinrich Korner and Dirk H Busch Magdalena Nauerth, Kristof Wing, Heinrich Korner and Dirk H Busch
Cytotoxic lymphocytes are critical for fighting viral and certain bacterial infections. Therefore, assessing the quality of cytotoxic T cell responses might have important clinical implications. TCR-pMHC binding (avidity) is a key determinant of T cell quality. Here we review currently available technologies for the measurement of TCR-pMHC avidity and their potential relevance for translational applications. .. View More»
DOI: 10.4172/1948-5948.1000275