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Lim TO
Lim TO
Malaysia
Publications
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Research Article
Clinical Outcome of Autologous Cultivated Limbal Epithelial Transplantation Therapy for Patients with Ocular Surface Disease
Author(s): Umapathy T, Alias R, Lim MN, Alagaratnam J, Zakaria Z and Lim TO Umapathy T, Alias R, Lim MN, Alagaratnam J, Zakaria Z and Lim TO
Introduction: Cultivated Limbal Epithelial Cells Transplantation (CLET) has been proven effective in reconstructing cornea surface of Limbal Stem Cell Deficiency (LSCD). To better understanding the potential and risk of this treatment in our current setup, we conducted a phase I clinical trial and determined the outcome of cultivated limbal epithelial transplantation for Ocular Surface Disease (OSD). Methods: Prospective interventional trial was conducted in Hospital Kuala Lumpur, Malaysia. Fourteen eyes of 14 patients with limbal stem cells deficiency: chemical injury (6), advanced pterygium (4), advanced Vernal Kerato Conjunctivitis (VKC) (2), Persistent Epithelial Defect (PED) (1) and Ocular Cicatricial Pemphygoid (OCP) (1) were selected according to the inclusion/exclusion criteria. Autologous cornea limbal.. View More»
DOI: 10.4172/2157-7633.1000248