Journal of Stem Cell Research & Therapy

Li Zhang

Publications

• Review Article
  MicroRNAs in Endothelial Development and Differentiation
  Author(s): Yijiang Zhou, Feng Yang, Yutao Wu, Mei Yang, Qingzhong Xiao and Li ZhangYijiang Zhou, Feng Yang, Yutao Wu, Mei Yang, Qingzhong Xiao and Li Zhang
  
  Endothelial integrity or homeostasis is not only essential for regulating arterial activity and vascular tone under physiological conditions, but also critical for triggering various cardiovascular diseases including atherosclerosis and balloon angioplasty if such a balance has been impaired. Moreover, endothelial cell development and differentiation are key steps during embryogenesis and involves co-ordinations of diverse signaling molecules and transcription factors. Therefore, characterizing the molecular mechanisms underlying endothelial differentiation and development will not only improve our understanding of pathogenesis of vascular disease, but also facilitate our ability in generation of vessels cells from pluripotent stem cells for therapeutic purpose. MicroRNAs, a class of small, non-coding RNAs, have been extensively implicated in the regulation of various aspects of biolo.. View More»
  DOI: 10.4172/2157-7633.1000191

  Abstract PDF