Journal of Allergy & Therapy

Leila Emma D’Urbano

Publications

• Research Article
  Eosinophilic Esophagitis and Ige-Mediated Allergy in Children: Specific Ige by Component-Based-Allergen Microarray
  Author(s): Francesca Rea, Leila Emma D’Urbano, Rosa Luciano, Marta Muraca, Luigi Dall’Oglio, Giovanni Cavagni and Paola De Angelis Francesca Rea, Leila Emma D’Urbano, Rosa Luciano, Marta Muraca, Luigi Dall’Oglio, Giovanni Cavagni and Paola De Angelis
  
  Background: Atopy is prevalent in eosinophilic esophagitis (EoE) but the relative role of airborn and food allergens in the etiopathogenesis is still incompletely understood; allergic immediate and delayed reactions are involved. Objective: We characterized the sIgE profile by a component-based allergen microarray with highly purified allergens in EoE in comparison with traditional sIgE assay and we evaluated a possible correlation between clinical features and sIgE results. Methods: In 30 consecutive patients diagnosed with EoE, three diagnostic tests were performed: skin prick test (SPT), ImmunoCAP sIgE and an allergen component microarray chip called ImmunoCAP ISAC. The ISAC chips cover 103 recombinant or purified allergen molecules including food, airborn and cross-reactive allergens. Results: Out of th.. View More»
  DOI: 10.4172/2155-6121.1000180

  Abstract PDF