Journal of Stem Cell Research & Therapy

Khaled Makboul

Publications

• Research Article
  Role of Autologous Bone Marrow Stem Cell Transplantation in the Treatment of Active Ulcerative Colitis
  Author(s): Alaa E Ismail, Mohsen M Maher, Wesam A Ibrahim, Shereen ASaleh, Khaled Makboul, Doaa Zakaria Zaki, Marina Nashed, Nehal Ibrahim and Mohammed Fathy Alaa E Ismail, Mohsen M Maher, Wesam A Ibrahim, Shereen ASaleh, Khaled Makboul, Doaa Zakaria Zaki, Marina Nashed, Nehal Ibrahim and Mohammed Fathy
  
  Background: Stem cell therapy was suggested to improve the quality of life to patients of UC through its powerful immunomodulatory effects and its ability to stimulate regeneration of intestinal mucosa. Aim of the work: To evaluate autologous bone marrow stem cells transplantation as a treatment option for cases of active ulcerative colitis in comparison with the conventional treatment, and to evaluate its safety and feasibility. Patients and methods: 10 patients of active ulcerative colitis were intravenously injected with autologous bone marrow mononuclear layer containing stem cell and continued on their conventional treatment. Clinical, laboratory and endoscopic assessment of disease severity were done before and after 3 months after SCT. Results: There was statistically significant improvemen.. View More»
  DOI: 10.4172/2157-7633.1000313

  Abstract PDF