Kazuhiko Nakagawa
Japan
Short Communication
Novel Drug Development of the Next-Generation T790M Mutant Specific
Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for the
Treatment of Advanced Non-Small Cell Lung Cancer
Author(s): Toshio Shimizu and Kazuhiko Nakagawa
Toshio Shimizu and Kazuhiko Nakagawa
Lung cancer is a leading cause of cancer death worldwide. Lung cancer accounts for over 1 million mortalities annually and non-small cell lung cancer (NSCLC) accounts for almost 85% of all cases. Epidermal growth factor receptor (EGFR) mutations are found in approximately 10% and 30% of patients with NSCLC in North American/European and East Asian countries, respectively.
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DOI:
10.4172/2161-1009.1000258