Jörg Schnitker
Germany
Research Article
Tolerability of the SQ-Standardised Grass Sublingual Immunotherapy Tablet in Adult Patients during Routine Administration: A Non-Interventional Observational Study
Author(s): Hans-Georg Vitzthum, Hendrik Wolf, Jörg Schnitker and Eike Wüstenberg
Hans-Georg Vitzthum, Hendrik Wolf, Jörg Schnitker and Eike Wüstenberg
Objective: The SQ-standardised grass sublingual immunotherapy (SLIT) tablet, GRAZAX® (ALK, Denmark) has been shown to be efficacious and well tolerated in a large number of clinical trials performed in Europe and USA. The aim of this study was to investigate the administration of the SQ grass SLIT-tablet in a real life setting.
Methods: This study was non-interventional, open-label, observational including 1,109 patients from 434 clinics in Germany treated between November 2006 and February 2009 with the SQ grass SLIT-tablet. Patients were followed at visits every 3 months for 9-12 months after start of therapy. Assessments included tolerability, compliance, patient satisfaction and treatment effect. Adverse drug reactions (ADRs) reported were coded by using the Medical Dictionary for Regulatory Activities (MedDRA).
Results: A total of 534 (48.2%) patients expe.. View More»
DOI:
10.4172/2155-6121.1000198