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Jostein Halgunset
Jostein Halgunset
Norway
Publications
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Research Article
Carcinoma Metastasis-An Approach to Models
Author(s): Haakon Skogseth, Kåre E. Tvedt and Jostein Halgunset Haakon Skogseth, Kåre E. Tvedt and Jostein Halgunset
Background: Epithelium is separated from other tissues in the body by the basal membrane. When respecting this boundary, atypical epithelial growth does not cause serious illness in most cases. Therefore, carcinoma in situ is considered to be a non-malignant condition. However, the situation is quite different if the epithelial cells do not respect the natural boundaries in the tissue, a condition that is often referred to as cancer. Uncontrolled invasive growth is indeed the main characteristic of malignancy, and metastasis is in most cases the reason why cancer patients die. Materials and methods: The purpose of this article is to highlight how carcinoma cells, nature, can be classified in three steps, in respect to the first local infiltration of malignant epithelium. The literature referred to is selecte.. View More»
DOI: 10.4172/2157-2518.1000119