Journal of Nanomedicine & Nanotechnology

Joshi KA

Publications

• Research Article
  Gloriosa superba Mediated Synthesis of Silver and Gold Nanoparticles for Anticancer Applications
  Author(s): Sougata Ghosh, Harke AN, Chacko MJ, Gurav SP, Joshi KA, Dhepe A, Dewle A, Tomar GB, Kitture R, Parihar PS, Banerjee K, Kamble N, Bellare J and Chopade BASougata Ghosh, Harke AN, Chacko MJ, Gurav SP, Joshi KA, Dhepe A, Dewle A, Tomar GB, Kitture R, Parihar PS, Banerjee K, Kamble N, Bellare J and Chopade BA
  
  Designing of novel environmentally benign route for synthesis of nanoparticles is a prerequisite for developing nanomedicine. Medicinal plants serve as rich source of diverse phytochemicals which not only synthesizes but also stabilizes the bioreduced nanoparticles. Herein we report for the first time the anticancer activity of gold and silver nanoparticles synthesized employing Gloriosa superba tuber extract. The synthesis was found to be rapid and efficient which completed within 5 h. Optimum concentration of AgNO3 was found to be 3 mM for synthesis of AgNPs while for AuNPs it was found to be 4 mM. Higher temperature facilitated the biosynthesis process, optimum being 50°C. High resolution transmission electron microscopy revealed that the AgNPs were smaller in a range from 3 to 20 nm, majority being spherical in shape. AuNPs were of exotic shapes li.. View More»
  DOI: 10.4172/2157-7439.1000390

  Abstract PDF