Dentistry received 2249 citations as per Google Scholar report
José Orestes Del Ciampo
Brazil
Research Article
The Therapeutic Use of Propolis Extract in Alveolar Bone Contaminated with Bacterial Endotoxin
Author(s): Yamba Carla Lara Pereira, João Paulo Mardegan Issa, Evandro Watanabe, Glauce Crivelaro Nascimento, Mamie Mizusaki Iyomasa, José Orestes Del Ciampo and Edilson Ervolino4
Yamba Carla Lara Pereira, João Paulo Mardegan Issa, Evandro Watanabe, Glauce Crivelaro Nascimento, Mamie Mizusaki Iyomasa, José Orestes Del Ciampo and Edilson Ervolino4
Propolis is a resinous substance obtained by bees, whose antibacterial, anti-inflammatory, antiviral, antifungal, immune stimulant, and local anesthetic wound healing properties have been considered for clinical practice. In particular, its anti-inflammatory and antibacterial characteristic seems to be a novel target for infectious process from dental origin. This work aimed to evaluate the propolis antibacterial potential against a bacterial endotoxin on dental alveoli. First, some properties of green propolis extract were analyzed (in vitro): 1) physicochemical profile 2) Minimum Inhibitory Concentration (MIC) against endotoxin from Gram negative Escherichia coli, and 3) its immunoregulatory activity on leukocytes from the spleen of rats. Then, an inflammatory process was induced in rats by a contamination with lipopolysaccharide (LPS) that is recognized as an endotoxin. For this pu.. View More»
DOI:
10.4172/2161-1122.1000473