Gerontology & Geriatric Research

Jonathan W Goldman

Publications

• Review Article
  Low Elderly Participation in Non-Small Cell Lung Cancer Clinical Trials
  Author(s): Amy L Cummings, Melody Mendenhall and Jonathan W GoldmanAmy L Cummings, Melody Mendenhall and Jonathan W Goldman
  
  Background: Lung cancer, with a median age at diagnosis of 70 years, is the current leading cause of cancer mortality in the United States. A lack of elderly enrollment in lung cancer clinical trials, however, has led to difficulty establishing elderly guidelines for treatment and has been highlighted by the Institute of Medicine and the American Society of Clinical Oncology as a key area for improvement. While there have been few elderly-specific clinical trials investigating chemoradiotherapy in lung cancer, there have been no elderly-specific trials investigating targeted therapy or immunotherapy and little is known about elderly outcomes with these agents. Methods: PubMed was queried for phase I clinical trials involving non-small cell lung cancer (NSCLC) in English in the past five years. Of these 192 studies, 49 investigated targeted therapy and/or immunotherapy without protocol.. View More»
  DOI: 10.4172/2167-7182.S4-006

  Abstract PDF