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John K. Triantafillidis
John K. Triantafillidis
Associated Professor "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania. Head, Department of Gastroenterology and Center for Inflammatory Bowel Disease,"Saint Panteleimon" General Hospital, Nicea,
Greece
Publications
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Review Article
The Role of Pre- and Probiotics in the Treatment of Inflammatory Bowel Disease
Author(s): John K. Triantafillidis, Filippos Georgopoulos and Emmanuel MerikasJohn K. Triantafillidis, Filippos Georgopoulos and Emmanuel Merikas
Many patients with inflammatory bowel disease use alteranative therapy, mainly probiotics and synbiotics, to manage this intestinal condition. Despite widespread use of these natural therapies by patients, health care providers may be unfamiliar with probiotics as a treatment modality. This review describes the rationale for use of probiotics in patients with active or inactive inflammatory bowel disease, their mechanism(s) of action, and recent controlled clinical studies in which efficacy of probiotics, prebiotics and synbiotics in patients with active or inactive inflammatory bowel disease has been explored. Certain probiotics, particularly E. coli Nissle 1917 and a multi-agent mixture VSL#3, may be benefit patients with UC or pouchitis, while LactoBacillus rhamnosus GG appears less useful. In general, probiotics show potential for therapeutic application mainly in pouchitis and to.. View More»
DOI: 10.4172/1948-5948.S1-005